Posting because it's a "war on some drugs" issue: Few people have done as good a job of showing the harms caused by drug prohibition as Jeffrey Singer, senior fellow at the Cato Institute. Here, you can see Dr. Singer debate Dr. Adriane Fugh-Berman on "Did Doctors Overtreating With Opioids Cause the Overdose Crisis? A Soho Forum Debate." It's also available as a Soho Forum podcast, which is how I listened to it during a long car drive (it's about one hour, twenty minutes long).
I thought Dr. Singer won, but apparently the audience thought both did a good job, which I guess shows that both views are adequately presented. There's a particularly good bit in which Singer explains why he believes all drugs should be legalized.