While there is work being done on the "longevity" and "space migration" parts of SMILE, the Timothy Leary formula for a future that features longer human lifespans, intelligence increase and space migration, it seems to be the intelligence increase part that seems to be advancing rapidly, in the form of artificial intelligence.
Jonathan Swift was one of Robert Anton Wilson's favorite authors. If I remember correctly, when RAW was living in Ireland, he made a point of reading all of Swift's work.
Now blogger and economics professor Tyler Cowen has announced he plans to interview an AI version of Jonathan Swift as part of his "Conversations with Tyler" interview series. I don't know how well the interview will turn out, but certainly we live in interesting times.